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Multimeric Biotherapeutics

Multimeric Biotherapeutics

FortiVac Vaccine Platform Technology

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Publications & Patents

Publications

Multimeric Soluble CD40 Ligand and GITR Ligand as Adjuvants for Human Immunodeficiency Virus DNA Vaccines G.W. Stone et al., J Virol 80:1762-1772, 2006.

Design of CD40 Agonists and their use in growing B cells for cancer immunotherapy. R.S. Kornbluth, M. Stempniak, G.W. Stone. Int Rev Immunol 31(4):279-288, 2012.

Vaccination with a fusion protein that introduces HIV-1 Gag antigen into a multi-trimer CD40L construct results in enhanced CD8+ T cell responses and protection from viral challenge by vaccinia-Gag S.Gupta et al. J Virol 88:1492-1501, 2014.

Patents

FortiVac issued patents, expiring 03/16/2034

US10072064B2, Composition comprised of antigen linked to a TNF superfamily ligand

US10774149B2, Composition comprised of antigen linked to a TNF superfamily ligand

Corresponding patents have issued at EPO, Canada, Spain, Australia, Denmark, Poland, and elsewhere

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